Our Innovative Technology

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Holloid offers a novel type of microscope/cytometer and an associated label-free technique that provides image-based data on colloids. This technique does not require a priori assumptions while providing statistics on individual objects. 

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Holloid provides real-time multi-dimensional data on physical characteristics. We can quantify the following physical properties in-real-time for all objects:

• Static properties (require snapshots only):

  • number

  • size

  • shape

  • eccentricity

  • amount of scattered light (dry mass)

  • inner structure (of cells: centrosome, inclusion bodies, etc.)

• Dynamic properties (require multi-image acquisition, “movies”):

  • translational diffusion (hydrodynamic size)

  • rotational diffusion (asymmetric objects)

  • sedimentation rate (density)

  • interaction potentials

including motion and interactions, of cells and other colloids, based on 3D imaging, with the throughput of cytometry.