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Real-Time Process Intelligence for the Pharma and Biotech Industry

Problems we solve

  • Microbial contamination in bioreactors often goes undetected until product loss occurs.

  • No real-time sterility verification of equipment, media, or ingredients.

  • Delayed lab results slow down decision-making in critical phases.

  • Inability to track microbial subpopulations or phenotype shifts.

  • High labor costs and limited skilled microscopy staff availability.

  • Rare contaminants or early infections are hard to detect.

  • Lack of data to optimize yield or identify process drift.

  • Regulatory hurdles in proving sterility without frequent lab testing.

How Holloid helps:

  • Install Hollometers in bioreactors or upstream/downstream lines to monitor all microorganisms in real time.

  • Detect contamination early — before quality or yield is compromised.

  • Continuously track phenotype evolution and microbial dynamics.

  • Replace periodic lab sampling with 24/7 full-volume insights.

  • Enable automated process control and generate QA/compliance reports.

  • Allow for sterile batch release decisions in minutes instead of hours.

  • Scale across lines using low-cost sensors and cloud-based analytics.

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